Saint-Joseph-de-Coleraine (French pronunciation: [sɛ̃ ʒozɛf də kɔlʁɛn]) is a municipality in the Municipalité régionale de comté des Appalaches in Quebec, Canada.

It is part of the Chaudière-Appalaches region and the population is 2,018 as of 2009.

It is named after Saint Joseph, father of Jesus, and the town of Coleraine in County Londonderry, Northern Ireland.