Saint-Marc-Jaumegarde (French pronunciation: [sɛ̃ maʁk ʒomgaʁd]; Provençal: Sant Marc de Jaumegarda) is a commune in the Bouches-du-Rhône department in southern France.

The commune includes Bonfillons, Roussillier, Plan de l'Orgue, Savoyards, and Bourg.

There are two man-made lakes, namely Bimont and Zola, and the streamlet, Prignon.

In 1239, the land was given to the Lord of Esparon by Ramon Berenguer IV, Count of Provence.

In 1723, Saint-Marc was sold to the Meyronnets, a family of advisors in the Provence Parliament.