St. Agnes Academy is a Dominican college-preparatory school for young women grades 9 through 12[3] in the Chinatown area and in the Greater Sharpstown district of Houston, Texas.

[3] Pauline Gannon, a Dominican Sister, founded St. Agnes Academy in 1905.

[3] St. Agnes opened on February 11, 1906, at 3901 Fannin Street[3] in what is now considered to be Midtown.

In 1974 Texas Monthly stated that St. Agnes had an image of being for "older Catholic families" since many alumnae of the school sent their daughters to attend St.

[6] The magazine stated that students from both St. Agnes and Duchesne, another Houston-area Catholic girls' school, originated from "mostly business and professional people with money.