In 1903, permanency was assured when Father Roche bought a block of land at Austin and Hadley and constructed Houston's first College Preparatory School for boys.

O'Rourke, C.S.B., educator and author, St. Thomas High School in 1940 moved to the current site on the bank of Buffalo Bayou.

During Houston's 20th century growth into a focus of world culture, St. Thomas High School has trained men of vision and responsibility, winners of national and international fame; statesmen, churchmen, artists, historians, athletes, civic and business leaders, industrial pioneers, and citizens of many talents.

The campus is self-contained with a fine arts center, computer lab, library, competition gymnasium, baseball field, chapel, and stadium, most housed in distinguished Texas Cordova Shell Stone[2] buildings.

David Thompson, the HISD board attorney, stated that both bidders violated the district's code of silence policy.

[11] St. Thomas High School is situated west of Downtown Houston on the wooded banks of Buffalo Bayou at the corner of Memorial Drive and Shepherd.

"[14] The Joplin Campus includes strength/conditioning and sports medicine facilities as well as 20,000 square feet (1,900 m2) locker rooms for basketball and wrestling teams.

Albert Mitchell (principal of Central Catholic, San Antonio) St. Thomas' last year of competition in the T.C.I.L.

The athletic department provides 12 different programs which are: Baseball, Basketball, Cross-Country, Football, Golf, Lacrosse, Rugby, Soccer, Swimming, Tennis, Track & Field, and Wrestling.

Currently, St. Thomas competes in the Texas Association of Private and Parochial Schools (TAPPS).

In May 2008 the school hired Craig Biggio, the former Houston Astros second baseman and Hall of Famer, as head baseball coach.