St. Anthony Catholic High School was founded in 1903 by the Oblates of Mary Immaculate as a junior seminary.

St. Anthony Catholic High School also offers admission to international students in grades 9–12.

[8] St. Anthony is a college-preparatory institution offering a variety of courses, including Pre-Advanced Placement (PAP), Advanced Placement (AP) and dual credit courses through the University of the Incarnate Word Senior Connection program.

Offerings include Texas Education Agency endorsements in Arts & Humanities, Business and Industry, Multidisciplinary Studies, Public Service and STEM.

[9] The Brainpower Connection is a group of elementary and secondary schools affiliated with the University of the Incarnate Word providing an educational pathway starting in pre-kindergarten and going through PhD programs.