Saint Floriano is a tempera and gold panel painting (79 × 55 cm) by Francesco del Cossa, created circa 1472 and on display at the National Gallery of Art in Washington.

[1] Francesco del Cossa was newly arrived in Bologna when he received from a commission from the Griffoni family for an altarpiece for the chapel in the Basilica of San Petronio, made in collaboration of another painter from Ferrara, Ercole de' Roberti.

[citation needed] The basis of the panel depicts Saint Florian standing holding a sword with one foot propped up on a stone parapet.

[citation needed] The saint holds a red rose in his hand and the lace hanging from his neck recalls his martyrdom, drowning tied to a millstone.

[citation needed] Reflecting the influence of Piero della Francesca, del Cossa's rendition of Florian figure is solemn and regal with attention is given to the anatomical and naturalistic rendering of the subject.