As with many upper-class Montreal institutions, the Saint James's Club underwent a significant upheaval during the Quiet Revolution of the 1960s and 1970s, when much of the city's Anglo-Scottish establishment relocated to Toronto.

In recent decades the club has reinvented itself as a predominantly Francophone institution.

[1] In 1864 the club opened its original clubhouse, designed by John William Hopkins and Frederick Lawford, at the northwest corner of Dorchester Boulevard and University Avenue.

[3] In 1960 the club partnered with the Yale Building Corporation to construct a combination club and office building, designed by Durnford Bolton Chadwick and Ellwood, at 620 Dorchester Boulevard West.

The first three floors were to be occupied by the club while the upper ten storeys were office space.