[9] In its early days, Pitchfork writer Brandon Stosuy booked bands such as Converge, Deafheaven and Iceage to play the venue because, in his words, "if you’re into loud music, and you live in New York, it’s where you want to go to see a show.

[10] On April 10, 2014, the surviving members of Nirvana played an invite-only show at Saint Vitus directly after their Rock and Roll Hall of Fame induction ceremony at Barclays Center.

[11] In April 2016, Saint Vitus celebrated its five-year anniversary with five nights of shows featuring headlining sets from Pallbearer, Corrosion of Conformity, Royal Thunder, and 13th Chime.

[16] In 2023, the venue announced a 346-page book by photographer and employee Nathaniel C. Shannon, Saint Vitus Bar: The First 10 Years: An Oral and Visual History, featuring essays and interviews from figures including Dave Mustaine, Laura Jane Grace and Chuck Klosterman.

[17][18] On February 16, 2024, Saint Vitus was indefinitely shut down by the New York City Department of Buildings for multiple violations, including the absence of maximum occupancy signs and improper certifications for assembly and drinking.

"[20] Several artists and bands who played at Saint Vitus, including Thursday, Chelsea Wolfe, Ethel Cain and Saetia, paid tribute to the venue on social media.