Salem High School is a comprehensive public high school located in Salem, Fulton County, Arkansas, United States.

The assumed course of study for Salem students follows the Smart Core curriculum developed by the Arkansas Department of Education (ADE), which requires students complete 22 units prior to graduation.

Students complete regular coursework and exams and may elect to take Advanced Placement (AP) courses and exams with the opportunity for college credit.

The Salem Greyhounds compete in interscholastic activities within the 2A Classification—the state's second smallest classification—via the 2A Region 2 Conference administered by the Arkansas Activities Association.

The Greyhounds field teams in football, golf (boys/girls), cross country (boys/girls), basketball (boys/girls), cheer, baseball, softball, track and field (boys/girls), and Volleyball (girls).