Salt-and-pepper chromatin

In pathology, salt-and-pepper chromatin, also salt-and-pepper nuclei and stippled chromatin, refers to cell nuclei that demonstrate granular chromatin (on light microscopy).

[1] Salt-and-pepper chromatin is typically seen in endocrine tumours such as medullary thyroid carcinoma, neuroendocrine tumours[2] and pheochromocytoma.

[3] This article related to pathology is a stub.

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Well-differentiated neuroendocrine tumor with salt-and-pepper chromatin, seen on H&E stain and Pap stain , and actual salt and pepper for comparison.