Salt River is a river in Canada whose source is McNeil Lake in Wood Buffalo National Park in northern Alberta.

It enters the Slave River north of Fort Smith, Northwest Territories.

[1] The main tributaries are Brine Creek (mouth coordinates 59°56′46.7″N 112°16′14.7″W / 59.946306°N 112.270750°W / 59.946306; -112.270750) and Loop Creek (mouth coordinates 59°39′31.2″N 111°55′14.5″W / 59.658667°N 111.920694°W / 59.658667; -111.920694).

A Roman Catholic mission was in the village from 1850[3] until 1876 when it moved to Fort Smith.

Salt deposits were collected from the banks during the fur trade era.