In 1999, Santana collaborated with his father on composing the Grammy winning track "El Farol" on the album Supernatural.

His musical roots stem from a firsthand education from his grandfathers, Saunders King and Jose Santana, his father, Carlos, as well as the music of jazz artists John Coltrane, Herbie Hancock, Thelonious Monk, and Oscar Peterson and a healthy implementation of contemporary hip-hop acts like Atmosphere, Ozomatli.

He enlisted underground legends Del the Funky Homosapien, Money Mark[7] (Beastie Boys), and GZA[8] to help him with the album's production.

The synergy between Salvador and Del, along with the eclectic and fresh sound of the Remixes project was the inspiration for the new musical direction in the studio for his sophomore release.

These remix MP3s were wildly popular, appearing on tastemaker music sites such as Brooklyn Vegan, Pitchfork Media, and My Old Kentucky Blog.

Keyboard Magazine [10] declared that "Funkadelic and the Meters had a love child who was then raised by Esquivel in a space age bachelor pad full of analog synths."

For the keyboardist, making music is never about personal glory, but about lifting people up with humility, love, and positivity on a daily basis.

"[13] In 2014, Salvador was invited by producer Gerry Gallagher to record with Latin rock legends El Chicano as well as Alphonse Mouzon, Brian Auger, Vikki Carr, Alex Ligertwood, Ray Parker Jr., Lenny Castro, Vikki Carr, Siedah Garrett, Walfredo Reyes Jr., Pete Escovedo, Peter Michael Escovedo, Marcos J. Reyes, Jessy J and David Paich and is featured on keyboards on Gallagher written, arranged and composed "melodic rap" song called "Sunday Kind Of Mood" which is part of Gallagher's most recent studio album due out in 2019.

[15] Santana's latest project is a politically-charged album with fellow musician Asdrubal "Asdru" Sierra of the band Ozomatli, entitled RMXKNZ.