Salvatore Perugini (born 6 March 1978 in Benevento) is a former Italian rugby union player.

He previously played for Italian club Calvisano and French side Stade Toulouse.

In April 2010 it was announced he would move to the newly formed Aironi for the 2010/2011 season.

Perugini was selected to play for the Barbarians when they beat New Zealand in 2009.

This biographical article relating to Italian rugby union is a stub.