[citation needed] He has also made important contributions to the understanding of intracellular traffic and protein folding and is an influential leader in the field of the molecular genetics of human cancer.
[citation needed] Sambrook is a former director of research at the Peter MacCallum Cancer Centre in Melbourne.
[7] He was the founder and director of the Kathleen Cunningham Consortium for research into familial breast cancer, KConFab, that was established in 1995.
[8] Sambrook has published four editions of the best-selling, highly influential laboratory manual Molecular Cloning, the third in 2001 with David Russell[9] and the fourth in 2012 with Michael R.
[10] He is also co-editor of Inspiring Science: Jim Watson and the Age of DNA and Life Illuminated: Selected Papers from Cold Spring Harbor Volume 2, 1972–1994.