The next year, he and his teacher Hugo Kronecker were among the first to study (in 1883) esophageal manometry in humans.
[1] In the United States, where he practiced his profession in New York City, he went on to serve as consulting physician to Harlem Hospital.
In 1906 he was appointed head of the department of physiology and pharmacology at the Rockefeller Institute for Medical Research.
He was an elected member of both the United States National Academy of Sciences and the American Philosophical Society.
[2][3] During World War I, Meltzer was a major in the Medical Reserve Corps, and when the American Association for Thoracic Surgery was organized in 1918 he was elected president.