The Strong House is located southwest of downtown Vergennes, on the northwest side of West Main Street (Vermont Route 22A).

It consists of a 2+1⁄2-story main block, covered by a front-facing gabled roof, with integral flanking side-gable single-story ells.

The building corners are pilastered, with a dentillated entablature encircling the main block, and a pedimented gable with triangular fan window at its center.

The main entrance is in the rightmost bay of the 3-bay facade, recessed with sidelight and transom windows in an opening framed by pilasters and an entablature.

Strong was the grandson of one of the area's early settlers, and achieved prominence in the community as president of the Bank of Vergennes and of the Rutland and Burlington Railroad.