Samuel Simons (1792 – January 13, 1847) was a Democratic member of the United States House of Representatives from Connecticut's 4th congressional district from 1843 to 1845.
He was born in Bridgeport, Connecticut, where he pursued an academic course of study.
He studied medicine and commenced practice in Bridgeport, Connecticut.
In addition, he was the director of the Housatonic Railroad and a trustee of the Bridgeport Savings Bank.
After leaving Congress, he resumed the practice of medicine in Bridgeport, Connecticut, where he died in 1847.