San Alberto is a city in the Alto Paraná department of Paraguay.

It is one of the districts of Northern Alto Paraná and is located about 439 km.

San Alberto has seen a rapid development and today is the main city in Northern Alto Paraná.

The city was founded by Alberto Fernández Valenzuela, a captain of the Paraguayan navy, who was president of the Empresa Colonizadora Industrial Mbaracayu S.A., initially was known as Gleba 6 and belonged to the district of Hernandarias.

Agriculture is the main source of economic income of the district.