San Antonio is a locality in Santa Fe Province in northeastern Argentina.

These two localities form the urban conurbation of San Antonio-Castellanos.

The foundation of San Antonio is due to Eduardo Saguier's desire to found a colony, for which he appointed Juan Beapuy as administrator.

It is estimated that the name of the locality is due to the founder's devotion to Saint Anthony of Padua.

[4] This article about a place in Santa Fe Province, Argentina is a stub.