The Politana site of the San Bernardino de Sena Estancia is a California Historical Landmark.

In 1851 the property was subsequently sold to Charles C. Rich and Amasa Lyman, leaders of the San Bernardino settlement of the Church of Jesus Christ of Latter-day Saints, and occupied by Bishop Nathan C. Tenney from 1851 through 1859, when Dr. Ben Barton purchased it from the Mormons due to their return to Utah.

Since funds weren't available to restore "mere" ranchos, a great deal of artistic license was taken in the design of the new, six-room structure (including exhibit space and a residence for the site manager), which replaced what was left of the original chapel building.

Additionally, a freestanding campanario (bell wall) was constructed (similar to that at Mission San Antonio de Pala) even though none had existed previously.

It was a branch of the San Bernardino County Museum until it was transferred to the nonprofit Redlands Conservancy in November, 2018.