It stands in front of the Fenice Theater and adjacent to the Ateneo Veneto (the former Scuola grande di San Fantin).

Reconstruction was undertaken by the Pisani family, who installed in the church a miraculous icon of the Virgin they had obtained from the East.

Ten thousand ducats were willed for the church's reconstruction by Cardinal Giovanni Battista Zeno who died in 1501.

[1] Work on the church has been assigned or attributed to many architects, from Pietro Lombardo, Sebastiano Mariani, and later Jacopo Sansovino.

It had a Holy Family attributed to Giovanni Bellini, a Crucifixion by Lionardo Corona, and a Visitation of Mary to Elizabeth by Tintoretto.