California State Route 78 (east/west) and County Road S-2 (north/south) pass through the San Felipe Valley.
[2] On May 23, 2013 a CALFIRE controlled burn escaped containment, becoming the San Felipe Fire.
[5] The Sonora Road later became the route of Kearny and Cooke whose Mormon Battalion made Cooke's Wagon Road along the route from Yuma Crossing, that from 1849 was heavily traveled by Forty-niners and later immigrants to the state of California, and known as the Southern Immigrant Trail.
From 1861 to 1865 in the American Civil War the abandoned stage station was a military outpost of the Union Army called Camp San Filipe, a rest stop on the road between California and Fort Yuma and the Arizona and New Mexico Territories.
[2] Adjacent protected areas are the Volcan Mountains Wilderness Preserve Park on the west, and the Iipay Nation of Santa Ysabel Reservation on the northwest.