The route of the Tren Maya includes a 235 km (146 mi) section extending from Escárcega to Calkiní, and this section includes a station in San Francisco de Campeche.

[4] Andrés Manuel López Obrador announced the Tren Maya project in his 2018 presidential campaign .

The route of the new Tren Maya put San Francisco de Campeche on the route that would connect with Escárcega, Campeche and Mérida, Yucatán.

[5] At first, the station was expected to be built on land owned by the Ferrocarril Transístmico.

[6][7] Some time later, the location of the station was changed to be built on the Periférico in Campeche.