The narrow church or oratory of San Gaetano di Thiene is found in the middle of via dei Pispini in Siena, Italy.

This oratory of the aristocratic Contrada del Nicchio (Sea-shell) was built from 1683-1700.

Between 1686 -1705, Giacomo Franchini added much of the internal stucco decoration, including statues of Blessed Ambrogio Sansedoni (first niche on left); the second niche and almost in conversation with the first is St Gaetano (Saint Cajetan); on the right are St Vincenzo Ferrer (flame over head) and Blessed Giovanni Colombini with a crucifix in left hand.

The ceiling was frescoed with the Theological virtues by Giuseppe Nasini and his pupil Stefano di Francesco Marzi.

The work was completed in 1734 by Apollonio Nasini using designs and help by father Giuseppe Nicola.