It appears that the arrival of further relics and other events led to the construction of the present cathedral north of this location higher on the hill.
Associated with John the Baptist, this church putatively once held a relic of this saint, and still houses a large 16th-century font used for baptisms.
Since 2000, the church has been used as the putative locale or background of the long-running television series titled Don Matteo, which features the collaborations of a detective-priest and a bumbling carabinieri to solve moral and criminal problems afoot.
The first altarpiece on the left depicts the Baptism of Christ (16th century) attributed to Felice Damiani; this canvas was originally present in the town Duomo.
The second altarpiece on the left depicts an Annunciation (19th century) attributed to Camilla Filicchi, originally painted for another site, and installed here.
In the hexagonal chapel of the baptistry (assigned this purpose in 1829), damaged frescoes depict standing Saints Anthony of Padua and Bernardino of Siena and were attributed to Giacomo di Benedetto Bedi.