Sant'Adriano III Papa is a Roman Catholic church located on Via San Carlo in Spilamberto, province of Modena, region of Emilia-Romagna, Italy.
In 1863, the sculptor Prudenzio Piccioli and the wood-engraver Giuseppe Tacconi worked together in the Chapel of the Rosary.
Piccioli sculpted the statue of Saints Pope Pius V and Dominic, as well as reliefs with the Mysteries of the Rosary.
Giuseppe Obici completed a stucco St John the Baptist, submitted in 1852 as a model for a marble statue completed for Santa Maria sopra Minerva.
From 1890 to 1915, the painter Augusto Valli frescoes a number of works in the church including a Battle of Lepanto for the Chapel of the Rosary; a Vision of the Apocalypse for the cupola; a Communion of the Apostles for the half-dome of the apse; an Annunciation and angels for the nave ceiling; as well as Popes and Saints linked to Spilamberto.