San Isidro is a barrio in the island-municipality of Culebra, Puerto Rico.

Its population in 2010 was 16.

[3][4][5] It consists of a part of the island of Culebra in the northeast, and of islands and islets such as Roca Speck, Cayo Norte, Cayo Sombrerito, Cayos Geniquí, Cayo Tiburón, and Cayo Ballena.

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