San Pantaleo is an ancient church located on a piazza of the same name along Corso Vittorio Emanuele II in the Parione neighborhood of Rome, Italy.

By 1621, it was restored by the fathers of the Scuole Pie (Piarists) of St Giuseppe Calasanzio, who lived in the adjacent convent.

On the apse wall behind the main altar is a large marble bas relief depicting San Calasanzio presenting children to the Madonna and Child (1802) by Luigi Acquisti and commissioned by prince Giovanni Torlonia.

[9] In 1808, also under the patronage of Prince Giovanni Torlonia, a neoclassical facade was commissioned from the architect Giuseppe Valadier.

[10] The significance of the facade frieze not evident; it depicts a cornucopia Christian symbols, scrolls, books, and shields resembling a display of a triumphal procession.