San Pedro River (Spanish: Río San Pedro) is a river in the southwest of Camagüey Province, Cuba.

The watershed is polluted due to the discharge of poorly treated liquid waste from the city of Camagüey.

River El Bolsillo joins it just south of the confluence.

San Pedro River flows south to Jimaguayú Dam, then west, and empties into the Caribbean Sea about 40 km west of town of Vertientes.

This article related to a river in Cuba is a stub.