The San Raffaele Hospital, known in Italian as Istituto scientifico universitario San Raffaele or Ospedale San Raffaele (HSR), is a university hospital situated in Segrate, in the province of Milan, Italy.

It was founded in 1969 by don Luigi Maria Verzé, president of "Fondazione San Raffaele del Monte Tabor".

The facility is connected to the Milan Metro by the MeLA people mover.

The hospital is affiliated with the School of Medicine and the School of Nursing of the Vita-Salute San Raffaele University.

The HSR is divided in different sectors: