The San Remo Resolution passed on 25 April 1920 determined the allocation of Class "A" League of Nations mandates for the administration of three then-undefined Ottoman territories in the Middle East: "Palestine", "Syria" and "Mesopotamia".

The conference was attended by the four Principal Allied Powers of World War I who were represented by the prime ministers of Britain (David Lloyd George), France (Alexandre Millerand), Italy (Francesco Nitti) and by Japan's Ambassador Keishirō Matsui.

[3] On 6 January 1920 Hussein's son Prince Faisal initialled an agreement with French Prime Minister Georges Clemenceau which acknowledged "the right of the Syrians to unite to govern themselves as an independent nation".

The conference was attended by the allies, the US representative joining the meeting later in an observer capacity:[6] British Empire: France: Italy: Japan: Interpreter: United States of America (as observers): The peace treaty with Turkey, the granting of League of Nation mandates in the Middle East, Germany's obligations under the Versailles Peace Treaty of 1919, and the Allies' position on Soviet Russia.

Germany was called upon to carry out its military and reparation obligations under the Versailles Treaty, and a resolution was adopted in favor of restoring trade with Russia.

The Mandatory will be responsible for putting into effect the declaration originally made on the 8th [2nd] November, 1917, by the British Government, and adopted by the other Allied Powers, in favour of the establishment in Palestine of a national home for the Jewish people, it being clearly understood that nothing shall be done which may prejudice the civil and religious rights of existing non-Jewish communities in Palestine, or the rights and political status enjoyed by Jews in any other country.

Il sera tenu compte dans la composition de cette Commission des interets religieux en jeu.

[The Mandatory undertakes to appoint in the shortest time a special commission to study any subject and any queries concerning the different religious communities and regulations.

For France, the San Remo decision meant that most of its claims in Syria were internationally recognized and relations with Faisal were now subject to French military and economic considerations.

[19] France issued an ultimatum and intervened militarily at the Battle of Maysalun in July 1920, deposing the Arab government and removing King Faisal from Damascus in August 1920.

[20] Article 22 of the League of Nations Covenant, which contained the general rules to be applied to all Mandated Territories, was written two months before the signing of the Versaille Peace Treaty.