San Silvestro is a Roman Catholic parish church located on Via Sccaone, along SS120, in the town of Troina, in the province of Enna, region of Sicily, Italy.

A small church at this site, dedicated to St Bartholemew was present by the 13th-century; in this century, the tomb and body of St Silvester of Troina, a basilian monk and patron of the town, were putatively discovered.

A central nave is separated from the aisles by solid stone columns with Corinthian capitals.

The simplicity of the walls and the wooden choir stalls above a domed apse are completed in a late Renaissance style.

The tomb of St Sylvester of Troina is covered with a recumbent statue of white alabaster, attributed to followers of Antonello Gagini.