San Vicente (Spanish pronunciation: [sam biˈsente]) is a municipality in the San Vicente department of El Salvador.

It was founded by 50 Spanish families in 1635 under the Tempisque tree, which is still standing today.

One point of interest is the Tower of San Vicente, designed by French Architect Eugenio Basilio Crepiat (the Spanish version of his name), located at the center of the city in Cañas Park.

The city has several local festivals, which take place at Cañas Park.

San Vicente is situated in a volcanic region abounding in hot springs and geysers.