In 2019, she launched PanaGenius Inc. With Face2face Africa as its flagship brand, PanaGenius reaches over 2 million users each month via its online platforms and engages thousands more via events such as the Pan-African Weekend Conference in New York City and the national 30 Black Stars Conference & Awards.

Appiah was born in eastern Ghana in a small town in 1989,[1][2][3][4][5] immigrated to Italy at the age of 8,[3][6][5] and lived in Milan.

In 2011, Appiah and partner Isaac O. Babu-Boateng launched Face2Face Africa, a pan-African media company.

[1][2][3][6][5][9] Drawing from their experiences growing up as African immigrants in the United States, the two created an online platform and a print magazine in order to help rebrand the image of Africa within the global community.

Appiah has also hosted an online talk show,[6][10] interviewing among others Jesse Jackson, Alek Wek,[10] Femi Kuti,[10] Serge Ibaka, and Lira.