The junior line, or the Sanguszko-Kowelski, of Szymon Samuel Sanguszko, subsequently assumed the title Sanguszko-Lubartowicz, according to the erroneous assumption of their descent from Algirdas' younger brother Liubartas.

Prince Paweł Karol Sanguszko-Lubartowicz (1682–1752), a Court and Grand Marshal of Lithuania, greatly expanded his holdings through his second marriage with Marianna Lubomirska, heiress of Ostroh.

His son, Prince Roman Sanguszko, was a Polish officer who participated in the November Uprising, and was exiled to Siberia.

With the incorporation of Galicia into Soviet Ukraine after World War II, the Sanguszkos lost their Gumniska and Sławuta estates, as well as their palace in Lviv, and emigrated to Brazil.

By the late 20th century, the family was represented by a single descendant, Prince Paul (born 1973), who resides in São Paulo.