The Santa Casa de Misericórdia of Santo Amaro (Portuguese: Santa Casa de Misericórdia de Santo Amaro) is an 18th-century philanthropic and medical building in Santo Amaro, Bahia, Brazil.

The Santa Casa de Misericórdia of Santo Amaro faces the Parish Church of Our Lady of Purification in the Historic Center of Santo Amaro.

The structure was developed around a courtyard to facilitate illumination and air circulation.

This feature was common to large public buildings of the period, notably the Asilo Santa Isabela in Salvador and later in the Agricultural School of São Bento das Lages (Escola Agrícola de São Bentodas Lages) in São Francisco do Conde.

[1][2] The Santa Casa de Misericórdia of Santo Amaro was listed as a historic structure by the National Institute of Historic and Artistic Heritage in 1941 under inscription number 287.