At Ash Fork, Arizona, the SFP&P connected with Santa Fe's operating subsidiary, the Atlantic & Pacific Railroad mainline, that ran from California to Chicago.
The SFP&P's 195-mile (314 km) line extended the Santa Fe Railway south into Phoenix.
The SFP&P stopped operating the Phoenix & Eastern when Southern Pacific Railroad acquired the Phoenix–Winkelman line on March 13, 1907.
On November 1, 1905, the SFP&P began operating the Arizona & California Railway that ran from a connection with the Santa Fe Railway in the Mojave Desert at Cadiz, California, to a connection with SFP&P at Matthie, Arizona, (located between Prescott and Wickenburg).
The original mainline ran via Prescott, the Peavine Bypass runs from Paulden to Skull Valley farther west.