Santa Luzia is an island of the Barlavento archipelago in Cape Verde located between São Nicolau and São Vicente, the channel of Santa Luzia separates the island of São Vicente and is 8 km wide.

[3] Administratively, it is not part of any municipality, but in the public domain of the state of Cape Verde.

[4] Together with the islets of Ilhéu Branco and Ilhéu Raso, Santa Luzia is on the tentative list of UNESCO's World Heritage Sites.

[5] Santa Luzia, Ilhéu Branco and Ilhéu Raso were declared a protected area as Santa Luzia Nature Reserve (Reserva Natural Integral de Santa Luzia) in 1990.

Conus santaluziensis is a species of sea snails found in the waters of Santa Luzia.