Santa Maria Assunta di Castelnuovo is a Roman Catholic church located on Via Angelo Giunta in the town limits of Recanati, province of Macerata, in the region of Marche, Italy.
A church at the site was present by the mid-12th century, built initially in Romanesque-style and affiliated with a Benedictine monastery, derived and subsidiary to the Abbey of Fonte Avellana.
The gabled facade was refurbished in the thirteenth century: into the facade are inserted two Gothic round rose windows, one semicircular lunette window, and a rounded stone portal decorated with a bas-relief of the Madonna Enthroned with Archangels Michael and Gabriel (1253) sculpted by Mastro Nicola Anconetano.
The bell-tower at the rear of the church dates to the 12th century, and was found to have 15th-century fresco fragments inside that are attributed to Pietro da Recanati.
Among the paintings once in this church was a Transfiguration by Lorenzo Lotto and a polyptych by Guglielmo Veneziano, both housed by 12016 in the Pinacoteca of Villa Colloredo Mels.