Santa Maria College is an independent Roman Catholic single-sex primary and secondary day and boarding school for girls located in Attadale, a southern suburb of Perth, Western Australia.

Santa Maria College is a member of the Independent Girls Schools Sporting Association.

The following individuals have served as Principal of Santa Maria College: Before the current house system came into operation the students were divided into teams – which were essentially for sporting carnivals.

The houses were initially School (red), Mercian (white), Trinity (Blue), however, as the number of students increased a fourth team was added in 1963 – Xavier (gold) Santa Maria College, as with most Australian schools, utilises a House system.

Dillon, de la Hoyde, Frayne, Kelly, O'Donnell, and O'Reilly are named after six of the Sisters who journeyed to Western Australia from Ireland and set up the first Catholic High School in the state – Victoria Square School, now known as Mercedes College.

Each House competes to earn points towards the "McAuley Shield" through various interhouse events including: swimming, athletics, cross-country, volleyball, soccer, debating, and public speaking.

The arts festival required each house to prepare a short play to showcase their acting abilities.