In 1502, a half-dozen Florentine women retired to a nearby house bought for them by a wool merchant named Dionisio di Clemente.
During the sixteenth century, the convent was enlarged to cope with the increasing number of nuns (totaling 102 in 1561).
In 1785, as part of the reform of the established religious promoted by Grand Duke of Tuscany, Peter Leopold, the convent was transformed into a school.
The church had a Archangels Michele and Gabriello by Francesco Curradi and a Miracle by St Dominic by Matteo Rosselli.
The main altarpiece, by Domenico Puligo, has been interpreted as a Presentation of the Virgin at the Temple (1526-1527), but may symbolize the entry of girls into the nunnery, since at the front of the picture are Dominican Saints Antonino Pierozzi, Thomas Aquinas, and Vincent Ferrer on one side and St Helena, Catherine, and Lucy on the other.