Construction of the church was begun in 1643 with plans by Francesco Borromini,[1] annexed to an Augustinian nunnery that was founded by Camilla-Virginia Savelli Farnese, Duchess of Latera.

The convent underwent a number of tribulations during the nineteenth century, however, it was not deconsecrated in 1873, as were many other monasteries.

The Diocese presently lists the church as being in the care of the few remaining nuns of the order of Suore Oblate del Santo Bambino Gesù.

The monastery also served as a place to hide Jews from the fascist authorities active in the Holocaust during World War II.

The interior still contains some of the marble sculptural decorations plus a St Augustine and the Mystery of the Trinity by Carlo Maratta and a canvas by Marco Benefial.