The devotion to this image of the Madonna rose during the plague year of 1656, and further donations allowed the church to be built.
The miracles and intercessions by the Madonna are registered in a book kept in the parochial archive, plus evident in the numerous votive marble plaques in the church.
The church facade has a tall narrow scroll decoration, the interior follows a Greek cross plan with a central dome.
The church entrance has a number of works of art by the artist Gaspare Traversi, who is best known for his genre paintings.
The architect Lazzari designed the main altar, the interior balustrades, and the base of the funereal monument for Gennaro Acampora, rector of the church.