Santa Maria della Concezione dei Cappuccini (Our Lady of the Conception of the Capuchins) is a Roman Catholic church located at Via Vittorio Veneto, 27, just north of the Piazza Barberini, in Rome, Italy.

Pope Urban VIII blessed its first stone on October 4, 1626, after which his Capuchin brother Cardinal Antonio Marcello Barberini began constructing it.

The main altar is built in marble by order of Pope Urban VIII; his coat of arms can be seen at the base of the two columns.

[1] The first chapel on the right has a dramatic altarpiece of St. Michael the Archangel Defeating Satan (c.1635) by Guido Reni and Christ Mocked by Gerard van Honthorst.

The painting, completed in 1636, gave rise to a story that Reni had represented Satan—crushed under St Michael's foot—with the facial features of Cardinal Pamphilj in revenge for the slight.

The underground crypt is divided into five chapels, lit only by dim natural light seeping in through cracks, and small fluorescent lamps.

The crypt originated at a period of a rich and creative cult for their dead; great spiritual masters meditated and preached with a skull in hand.