Next to the lighthouse is the large Sanctuary, or Basilica, De Finibus Terrae ("End of the Land", 1720-1755), built to commemorate the passage of St. Peter here during his travel to Italy.
Punta Meliso promontory (the ancient Promontorium lapygium or Sallentinum) is the southeastern extremity of Italy — traditionally considered the lowest point of the geographical "heel" of Italian peninsula, as well as the meeting point of the waters from the Adriatic Sea and the Ionian Sea.
Santa Maria di Leuca's littoral is marked by numerous grottoes with Latin and Greek inscriptions.
Not far off Punta Ristola, at c. 85 m of depth, lies the shipwreck of the Italian submarine Pietro Micca, sunk during World War II with its crew of 58 men.
Santa Maria di Leuca was founded in fact in the early 1st century AD by some monks, after Saint Peter's passage.