On 24 June 1894, he fatally stabbed President Carnot after a banquet, to avenge the executions of anarchist bombers Auguste Vaillant and Émile Henry.

His father was a boatman who died of pellagra, at the time a common disease among farmers whose poor diet was often almost exclusively corn.

At ten years old, Sante Caserio left the family home and went to Milan, where he got a job as an apprentice baker and had his first contacts with anarchists.

In Milan he joined a small group called "On Foot" (a pè, at the time signifying "without money").

[2]He also stated to those in attendance:Well, if the rulers can use against us rifles, shackles and prisons, we must, we anarchists to defend our lives, we must stick to our principles?

His death mask was in the possession of Jean-Marie Le Pen, leader of the French party National Front.