At first, the group met in a chapel of Sant'Eustachio, but in 1622, the confraternity was bequeathed a property on the VIa di Torre Argentina.

[1] The already existing house chapel was converted into a church with a separate entrance in 1625, and given the dedication is because St Benedict started his monastic career at Norcia before moving to Montecassino.

This tondo is flanked by two diagonal strips of cornice each with a faint S-curve, and which join to it via tiny volutes.

The walls are painted to imitate green hanging curtains, with trompe-l'œil pilasters supporting an entablature with an inscription "Felix Nursiae tellus quae talem genuit alumnum" or "Happy land of Norcia, which gave birth to such a pupil".

There is a painting of the patrons over the altar, and over that a lunette containing stained glass showing the Madonna and Child being venerated by saints.