Santi Sergio e Bacco (Катедральний храм Святих мучеників Сергія і Вакха та Жировицької ікони Пресвятої Богородиці (Katedralnyi khram Sviatykh muchenykіv Serhіia і Vakkha ta Zhyrovytskoyi іkony Presviatoyi Bohorodytsі) is a Catholic church of the Byzantine Rite located on Piazza Madonna dei Monti in the rione of Monti in Rome, Italy.

Sergius and Bacchus which is located in Callinico," to which Pope Leo III (795–816) gave gifts (LP 98.24, 98.78), and the "monastery of Christ’s holy martyrs Sergius and Bacchus called Callinicum" to which Pope Benedict III (855–858) gave silver gifts including two chalices, a paten and incense boat (LP 106.26).

In 1413, the church of Sts Sergius and Bacchus stopped being associated with a monastery, since the Benedictine abbot and monks were replaced by an archpriest and secular clerics.

In 1622 it was entrusted by Pope Gregory XV (1621–23) to the Minim Friars of St. Francis of Paola who soon left it when they moved to another church near San Pietro in Vincoli.

Cardinal Antonio Barberini, titular of Sant'Onofrio al Gianicolo, in honor of Saints Sergius and Bacchus did this work.

[7] In 1718 an icon of Madonna and child is said to have been discovered under the plaster of a wall in the adjacent sacristy building and the next year it was removed and installed above the main altar of Sts.

[8][9] Using designs formulated by Francesco Ferrari in the first years of the 18th century, starting in 1741 reconstruction and redecoration of the church was undertaken to honor of the image of the Madonna.

Behind a modern wrought iron iconostasis, the high altar is set off by two fluted columns of verde antico marble with bronze Corinthian capitals designed by Filippo Barigioni (1690 –1753), a Roman artist who did other projects for Clement XI.

Basil, in 1819 recorded by inscription that Pope Pius VII (1800–23) in 1801 solemnly venerated the Madonna del Pascolo, which Clement XI had installed here.

Through the last years of Cardinal Slipyj, who died in 1984 aged 92, and the years of Myroslav Ivan Lubachivsky, who was appointed Slipyj's coadjutor bishop as Archbishop of Lviv in 1979, succeeded him at his death, and was made cardinal in 1985, the chancery was a central point in the West for contact with the underground Ukrainian Catholic Church in Ukraine and for advocating religious freedom under the Soviets, particularly at the time of Mikhail Gorbachev's policy of perestroika.

[13] The church and its guest accommodation hosted celebrations for the installation as Cardinal of Lubomyr Husar in 2001, Major Archbishop of Kyiv-Halychyna.

[14] The guest hotel, named St. Sophia, is conducted by a community of Ukrainian Greek Catholic nuns, the Sisters Catechists of Saint Anne.