The main 13th-century portal, with a pointed tympanum above, was refurbished by Pietro Bernardini with flanking baroque-style corinthian pilasters.
In the 1st altar on the right is a venerated icon of the Virgin covering her faithful with her cape, with another depicting the Marriage of Cannae by Benedetto Orsi.
The wooden 15th-century Madonna detta dell'Acquavino (Virgin of the Annunciation) sculpture has been attributed to Matteo Civitali.
The canvas in the choir depicting San Policronio and other Saints was painted by Ercole Bazzicaluva, who is best known for his engravings in the style of Callot, Stefano della Bella, and Cantagallina.
Between the two chapels on the left is a canvas depicting Jesus changing the heart of St Catherine of Siena by Jacopo Vignali, pupil of Rosselli.