Sao Nang Hearn Kham (Burmese: စောဝ်နန်းဟိန်ခမ်; 26 May 1916 – 17 January 2003) was the Mahadevi of Yawnghwe one of the most important Shan States.

Her husband Sao Shwe Thaik was the 23d and last Saopha of Yawnghwe and became the first President of Burma and she became the first First Lady of Myanmar.

Sao Nang Hearn Kham was the only woman in history of Burma to have held both the position of queen consort and first lady.

In post-independence Burma she became an MP for the constituency of Hsenwi between 1956 and 1960 and became known for her active role within the parliament under the administration of the prime minister U Nu.

Sao Nang Hearn Kham died on 17 January 2003 in exile in Canada at the age of 86.